Anti-P27 Polyclonal Antibody
應(yīng)用 IHC
稀釋比例IHC 1:50-200.
交叉反應(yīng)Human

產(chǎn)品型號(hào)：K106720P

更新時(shí)間：2022-08-15

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Anti-P27 Polyclonal Antibody

英文名稱(chēng)	Anti-P27 Polyclonal Antibody
宿主	Rabbit
別名	CDKN1B;CDKN4;KIP1;MEN1B;MEN4;P27;KIP1;P27KIP1
應(yīng)用	IHC
稀釋比例	IHC 1:50-200.
交叉反應(yīng)	Human
蛋白分子量	22kDa
Gene ID	1027
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	Recombinant protein of human P27
性狀	液體
Public Immunogen Range	Recombinant protein of human P27
Subcellular Locations	Nucleus
Swiss Prot	P46527
克隆類(lèi)型	Polyclonal Antibody
背景資料	This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4)