Anti-MCPIP1 Polyclonal Antibody
應(yīng)用 WB IHC
稀釋比例WB 1:500-2000. IHC 1:20-50.
交叉反應(yīng)Human

產(chǎn)品型號：K106615P

更新時間：2022-08-15

廠商性質(zhì)：生產(chǎn)廠家

訪問量：1150

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Anti-MCPIP1 Polyclonal Antibody

英文名稱	Anti-MCPIP1 Polyclonal Antibody
宿主	Rabbit
別名	dJ423B22.1;MCPIP;MCPIP1;dJ423B22.1;MCPIP;MCPIP-1;MCPIP1;Reg1
應(yīng)用	WB IHC
稀釋比例	WB 1:500-2000. IHC 1:20-50.
交叉反應(yīng)	Human
蛋白分子量	67kDa
Gene ID	80149
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human MCPIP1
性狀	液體
Public Immunogen Range	A synthetic peptide of human MCPIP1
Subcellular Locations	Cytoplasm Nucleus
Swiss Prot	Q5D1E8
克隆類型	Polyclonal Antibody
背景資料	Endoribonuclease involved in various biological functions such as cellular inflammatory response and immune homeostasis, glial differentiation of neuroprogenitor cells, cell death of cardiomyocytes, adipogenesis and angiogenesis. Functions as an endoribonuclease involved in mRNA decay. Modulates the inflammatory response by promoting the degradation of a set of translationally active cytokine-induced inflammation-related mRNAs, such as IL6 and IL12B, during the early phase of inflammation. Prevents aberrant T-cell-mediated immune reaction by degradation of multiple mRNAs controlling T-cell activation, such as those encoding cytokines (IL6 and IL2), cell surface receptors (ICOS, TNFRSF4 and TNFR2) and transcription factor (REL) (By similarity).