Anti-ERK1/2 Polyclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:500-2000.
交叉反應(yīng)Human Mouse Rat

產(chǎn)品型號：K106589P

更新時間：2022-08-15

廠商性質(zhì)：生產(chǎn)廠家

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標簽抗體血清球蛋白 IgG Polyclonal Antibody Antibody Monoclonal Antibody 一抗內(nèi)參抗體膠體金標記二抗生物素化二抗 RBITC熒光標記抗體二抗 FITC熒光標記抗體二抗免疫血清二抗純化抗體二抗 HRP標記二抗免疫球蛋白抗原IgG二抗

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Anti-ERK1/2 Polyclonal Antibody

英文名稱	Anti-ERK1/2 Polyclonal Antibody
宿主	Rabbit
別名	ERK;ERK-2;MAPK2;p38;p40;p41;p41mapk;p42-MAPK;P42MAPK;PRKM1;PRKM2
應(yīng)用	WB
稀釋比例	WB 1:500-2000.
交叉反應(yīng)	Human Mouse Rat
蛋白分子量	41kDa
Gene ID	5594
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	Recombinant protein of human ERK1/2
性狀	液體
Public Immunogen Range	Recombinant protein of human ERK1/2
Subcellular Locations	Cytoplasm Nucleus Cell membrane Cytoskeleton
Swiss Prot	P28482
克隆類型	Polyclonal Antibody
背景資料	Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. About 160 substrates have already been discovered for ERKs. Many of these substrates are localized in the nucleus, and seem to participate in the regulation of transcription upon stimulation.