Anti-GAD65 Polyclonal Antibody
應(yīng)用 WB IHC
稀釋比例WB 1:2000-5000.IHC 1:50-200.
交叉反應(yīng)Human Mouse Rat

產(chǎn)品型號：K106572P

更新時間：2022-08-15

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Anti-GAD65 Polyclonal Antibody

英文名稱	Anti-GAD65 Polyclonal Antibody
宿主	Rabbit
別名	GAD2;DCE2;MGC161605;MGC161607
應(yīng)用	WB IHC
稀釋比例	WB 1:2000-5000.IHC 1:50-200.
交叉反應(yīng)	Human Mouse Rat
蛋白分子量	65kDa
Gene ID	2572
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human GAD65
性狀	液體
Public Immunogen Range	A synthetic peptide of human GAD65
Subcellular Locations	Cytoplasm Cell membrane
Swiss Prot	Q05329
克隆類型	Polyclonal Antibody
背景資料	This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.