Anti-XIAP Polyclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human Mouse Rat

產(chǎn)品型號：K106527P

更新時間：2022-08-15

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Anti-XIAP Polyclonal Antibody

英文名稱	Anti-XIAP Polyclonal Antibody
宿主	Rabbit
別名	API3;BIRC4;hIAP-3;hIAP3;IAP-3;ILP1;MIHA;XLP2
應(yīng)用	WB
稀釋比例	WB 1:3000.
交叉反應(yīng)	Human Mouse Rat
蛋白分子量	54kDa
Gene ID	331
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human XIAP
性狀	液體
Public Immunogen Range	A synthetic peptide of human XIAP
Subcellular Locations	Cytoplasm Nucleus
Swiss Prot	P98170
克隆類型	Polyclonal Antibody
背景資料	This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.